Medical office space for lease in Grand Central
The Grand Central submarket is commuter-driven, with Metro-North access making it a default choice for firms with a suburban workforce. Park Avenue and Lexington carry the big blocks while the side streets hold efficient pre-built suites.
- Office stock
- 32.2M SF
- Office properties
- 129
- Largest office
- 51 East 42nd Street
- Transit
- 4 5 6 7 S at Grand Central
Building figures are existing stock from NYC PLUTO 26v2 tax lot records, not space on the market. More below.
On Leasemark No medical office space for lease and no requirements posted in Grand Central yet. Post yours and it is matched the day it goes up.
Nothing listed here yet
New medical spaces in Grand Central are matched to requirements the day they are posted. Post yours and be first in line.
For owners and brokers
Hear the moment a tenant looks for medical office space in Grand Central
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NYC tax lot records
Office buildings in Grand Central
What already stands here, from the city's own property data. Useful for sizing a search before a single space is listed.
- Office space
- 32.2M SF
- Properties with office space
- 129
- All commercial space
- 35.0M SF
- Built before 1940
- 75%
Largest office buildings
All 83 large commercial buildings in Grand CentralAge, height and zoning
- Median year built: 1926.
- Median height: 12 floors.
- Most common zoning districts: C5-3 (102), C5-2.5 (49), R8B (15).
- 14 lots are designated city landmarks.
Source: NYC Department of City Planning, PLUTO 26v2, pulled 2026-10-16. Counts cover tax lots with commercial floor area within about 0.4 mi of Grand Central's commercial core, and each lot counts toward one neighborhood only, so boundaries are approximate. Building figures are the city's floor-area estimates, not available space.
MTA station data
Subway stations in Grand Central
Every station within about 0.5 mi of Grand Central's commercial core, closest first. Stations joined by a free transfer count once.
- Stations
- 4
- Subway lines
- 10
- Fully accessible
- 3 of 4
- Closest
- Grand Central-42 St, 1 min walk
The 4 stations
- Grand Central-42 St
- 5 Av
- 51 St
- 47-50 Sts-Rockefeller Ctr
Lines
The 4, 5, 6, 7, B, D, E, F, M and S trains stop within about 0.5 mi of Grand Central's core.
Step-free access
- Grand Central-42 St (4 5 6 7 S) is fully accessible.
- 51 St (6) is fully accessible.
- 47-50 Sts-Rockefeller Ctr (B D F M) is fully accessible.
Source: Metropolitan Transportation Authority, MTA Subway Stations, pulled 2026-10-16. Walking times are straight-line estimates from the nearest point of Grand Central's commercial core (the same area as the building counts), so the street route is longer. Accessibility is the MTA's rating for the named station. PATH, LIRR, Metro-North and ferries are not in this data.
Before you sign
Plain-English guides to square footage, rent and lease terms in New York, and free calculators to run your own numbers.
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What does $/SF/yr mean? How to calculate rent per square foot
$/SF/yr is a year's rent for one square foot. How to turn it into a monthly bill, spot a monthly quote, and see what the rate leaves out before you compare spaces.
- Free calculator
Office space calculator
How many square feet your team needs, from headcount and layout to a rentable range.
- Free calculator
Commercial rent calculator
Turn a price per square foot into monthly and yearly rent, with increases, free rent and net effective rent.
- Free calculator
TI allowance calculator
A landlord's build-out allowance in dollars, what it covers of your budget and what the rest adds to the rent.
- Free calculator
Commercial Rent Tax calculator
Whether a Manhattan lease owes the city's Commercial Rent Tax, and roughly how much a year.
Questions about medical space in Grand Central
Is there medical space for lease in Grand Central right now?
No medical space for lease in Grand Central is listed on Leasemark right now. Post what you need and Leasemark matches you the day a space that fits is listed; your contact details stay private until you accept an intro. Owners and brokers can list a space here for free.
How much does medical space cost in Grand Central?
Pricing depends on building class, floor, condition and lease length. Post a requirement with your budget and Leasemark will match you with spaces that fit it as they are listed.
How do I find medical space in Grand Central that is not publicly listed?
Post a requirement on Leasemark. Owners and listing brokers see what you need (without your contact details) and can respond with spaces, including ones that are not on the market yet. You choose who gets an intro.
How much office space is there in Grand Central?
New York City's PLUTO tax lot data (26v2) records about 32.2 million square feet of office floor area across 129 properties in the part of Grand Central Leasemark covers. The largest by that measure is 51 East 42nd Street, at about 1.6 million square feet. That is the existing building stock, not space currently for lease.
What subway lines serve Grand Central?
Four subway stations sit within about 0.5 mi of Grand Central's commercial core, served by the 4, 5, 6, 7, B, D, E, F, M and S trains. The closest is Grand Central-42 St (4 5 6 7 S), roughly 1 minute on foot; then 5 Av (7 B D F M), 51 St (6 E F) and 47-50 Sts-Rockefeller Ctr (B D F M). Walking times are straight-line estimates from MTA station data.
Do tenants in Grand Central pay the NYC Commercial Rent Tax?
Yes, for larger leases. Grand Central is in Manhattan below 96th Street, where the city's Commercial Rent Tax applies. A tenant owes it only when base rent for the space is $250,000 a year or more. The tax is 6% of base rent after a 35% reduction, so 3.9% of rent, with a sliding credit between $250,000 and $300,000, and the Small Business Tax Credit wipes it out for businesses with total income of $5 million or less and base rent under $500,000.
Is it free to post on Leasemark?
Yes. Posting a space or a requirement is free. Contact details are only shared when both sides accept an intro.