Medical office space for lease in Murray Hill

Murray Hill is a residential-leaning neighborhood with a steady medical office and neighborhood retail market along Lexington, Third, and Second Avenues. It is close to the NYU Langone and Bellevue campuses.

Office stock
10.4M SF
Office properties
178
Largest office
622 Third Avenue
Transit
6 at 33 St

Building figures are existing stock from NYC PLUTO 26v2 tax lot records, not space on the market. More below.

On Leasemark No medical office space for lease and no requirements posted in Murray Hill yet. Post yours and it is matched the day it goes up.

Nothing listed here yet

New medical spaces in Murray Hill are matched to requirements the day they are posted. Post yours and be first in line. The labeled example below shows how a space appears here; it is not on the market.

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What a requirement here looks like

No live requirements in Murray Hill yet. These labeled examples show what tenants post. Owners: list a space and we match it against every new requirement automatically.

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NYC tax lot records

Office buildings in Murray Hill

What already stands here, from the city's own property data. Useful for sizing a search before a single space is listed.

Office space
10.4M SF
Properties with office space
178
All commercial space
18.1M SF
Built before 1940
69%

Largest office buildings

  1. 41 floors · built 1974
  2. 43 floors · built 1963
  3. 37 floors · built 1928
  4. 41 floors · built 1960
  5. 42 floors · built 1977
All 28 large commercial buildings in Murray Hill

Age, height and zoning

  • Median year built: 1920.
  • Median height: 5 floors.
  • Most common zoning districts: C1-9 (136), R8B (85), R10 (71).
  • Historic districts: Murray Hill Historic District (24 lots), Tudor City Historic District (6 lots), Murray Hill Historic District Extension (5 lots).
  • 14 lots are designated city landmarks.

Source: NYC Department of City Planning, PLUTO 26v2, pulled 2026-10-16. Counts cover tax lots with commercial floor area within about 0.4 mi of Murray Hill's commercial core, and each lot counts toward one neighborhood only, so boundaries are approximate. Building figures are the city's floor-area estimates, not available space.

MTA station data

Subway stations in Murray Hill

Every station within about 0.5 mi of Murray Hill's commercial core, closest first. Stations joined by a free transfer count once.

Stations
2
Subway lines
5
Fully accessible
1 of 2
Closest
Grand Central-42 St, 5 min walk

The 2 stations

  • Grand Central-42 St5 min walk · Accessible station
  • 33 St7 min walk · Not accessible

Lines

The 4, 5, 6, 7 and S trains stop within about 0.5 mi of Murray Hill's core.

Step-free access

  • Grand Central-42 St (4 5 6 7 S) is fully accessible.

Source: Metropolitan Transportation Authority, MTA Subway Stations, pulled 2026-10-16. Walking times are straight-line estimates from the nearest point of Murray Hill's commercial core (the same area as the building counts), so the street route is longer. Accessibility is the MTA's rating for the named station. PATH, LIRR, Metro-North and ferries are not in this data.

Before you sign

Plain-English guides to square footage, rent and lease terms in New York, and free calculators to run your own numbers.

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Questions about medical space in Murray Hill

Is there medical space for lease in Murray Hill right now?

No medical space for lease in Murray Hill is listed on Leasemark right now. Post what you need and Leasemark matches you the day a space that fits is listed; your contact details stay private until you accept an intro. Owners and brokers can list a space here for free.

Get matched in Murray Hill

How much does medical space cost in Murray Hill?

Pricing depends on building class, floor, condition and lease length. Post a requirement with your budget and Leasemark will match you with spaces that fit it as they are listed.

How do I find medical space in Murray Hill that is not publicly listed?

Post a requirement on Leasemark. Owners and listing brokers see what you need (without your contact details) and can respond with spaces, including ones that are not on the market yet. You choose who gets an intro.

How much office space is there in Murray Hill?

New York City's PLUTO tax lot data (26v2) records about 10.4 million square feet of office floor area across 178 properties in the part of Murray Hill Leasemark covers. The largest by that measure is 622 Third Avenue, at about 960,000 square feet. That is the existing building stock, not space currently for lease.

What subway lines serve Murray Hill?

Two subway stations sit within about 0.5 mi of Murray Hill's commercial core, served by the 4, 5, 6, 7 and S trains. The closest is Grand Central-42 St (4 5 6 7 S), roughly 5 minutes on foot; then 33 St (6). Walking times are straight-line estimates from MTA station data.

Do tenants in Murray Hill pay the NYC Commercial Rent Tax?

Yes, for larger leases. Murray Hill is in Manhattan below 96th Street, where the city's Commercial Rent Tax applies. A tenant owes it only when base rent for the space is $250,000 a year or more. The tax is 6% of base rent after a 35% reduction, so 3.9% of rent, with a sliding credit between $250,000 and $300,000, and the Small Business Tax Credit wipes it out for businesses with total income of $5 million or less and base rent under $500,000.

Estimate it with the Commercial Rent Tax calculator

Is it free to post on Leasemark?

Yes. Posting a space or a requirement is free. Contact details are only shared when both sides accept an intro.