Manhattan

Large commercial buildings in Harlem

Every office, retail and industrial building in Harlem with at least 100,000 square feet of that space, from the city's own tax lot records. Open one for its size, age, zoning and any space listed in it.

Buildings
16
Their floor area
2.6M SF
Largest
721 Esplanade Gardens Plaza
  1. 721 Esplanade Gardens PlazaOffice and commercial building · 294K SF office · 3 floors · built 2011
  2. 280 Street Nicholas AvenueShopping center · 248K SF retail · 4 floors · built 1998
  3. 450 West 126th StreetOffice building with commercial space · 235K SF office · 11 floors · built 2019
  4. 125 West 125th StreetOffice building with commercial space · 231K SF office · 19 floors · built 1972
  5. 55 West 125th StreetOffice building with commercial space · 181K SF office · 15 floors · built 1974
  6. 100 West 125th StreetShopping center · 161K SF retail · 6 floors · built 2013
  7. 2082 Adam C Powell BoulevardOffice building with commercial space · 151K SF office · 12 floors · built 1913
  8. 215 West 125th StreetOffice building with commercial space · 143K SF office · 6 floors · built 1971
  9. 105 West 125th StreetCommercial condominium · 142K SF office · 10 floors · built 2001
  10. 374 West 125th StreetOffice building · 125K SF office · 9 floors · built 2002
  11. 461 West 126th StreetOffice building with commercial space · 117K SF office · 11 floors · built 1980
  12. 51 West 142nd StreetSelf-storage building · 115K SF industrial and storage · 3 floors · built 1921
  13. 122 West 146th StreetWarehouse · 114K SF industrial and storage · 4 floors · built 2015
  14. 2926 Fredrick Douglass BoulevardSelf-storage building · 110K SF industrial and storage · 3 floors · built 2021
  15. 1916 Park AvenueOffice building · 107K SF office · 6 floors · built 1896
  16. 132 West 125th StreetOffice building with commercial space · 101K SF office · 6 floors · built 1940

Source: NYC Department of City Planning, PLUTO 26v2, pulled 2026-09-26. Sizes count each building's largest use (office, retail or industrial). Boundaries are approximate: each tax lot counts toward one neighborhood only. Only buildings with a street number and a leasable commercial building class are included.